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The Inflammasome and lupus- another innate immune mechanism contributing to disease pathogenesis?

PURPOSE OF REVIEW: The role of innate immunity in systemic lupus erythematosus (SLE) has been a rapidly expanding area of research over the last decade. Included in this rubric is the concept that activation of the inflammasome, a molecular complex that activates caspase-1 and in turn, the cytokines...

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Detalhes bibliográficos
Main Authors: Kahlenberg, J. Michelle, Kaplan, Mariana J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153426/
https://ncbi.nlm.nih.gov/pubmed/24992143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BOR.0000000000000088
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