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Tandospirone, a 5-HT(1A) partial agonist, ameliorates aberrant lactate production in the prefrontal cortex of rats exposed to blockade of N-methy-D-aspartate receptors; Toward the therapeutics of cognitive impairment of schizophrenia
Rationale: Augmentation therapy with serotonin-1A (5-HT(1A)) receptor partial agonists has been suggested to improve cognitive impairment in patients with schizophrenia. Decreased activity of prefrontal cortex may provide a basis for cognitive deficits of the disease. Lactate plays a significant rol...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153291/ https://ncbi.nlm.nih.gov/pubmed/25232308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2014.00291 |
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