α-Lipoic Acid Inhibits Helicobacter pylori-Induced Oncogene Expression and Hyperproliferation by Suppressing the Activation of NADPH Oxidase in Gastric Epithelial Cells

Hyperproliferation and oncogene expression are observed in the mucosa of Helicobacter pylori- (H. pylori-) infected patients with gastritis or adenocarcinoma. Expression of oncogenes such as β-catenin and c-myc is related to oxidative stress. α-Lipoic acid (α-LA), a naturally occurring thiol compoun...

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Hauptverfasser: Byun, Eunyoung, Lim, Joo Weon, Kim, Jung Mogg, Kim, Hyeyoung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152957/
https://ncbi.nlm.nih.gov/pubmed/25210229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/380830
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