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Flavonoids Are Inhibitors of Human Organic Anion Transporter 1 (OAT1)–Mediated Transport

Organic anion transporter 1 (OAT1) has been reported to be involved in the nephrotoxicity of many anionic xenobiotics. As current clinically used OAT1 inhibitors are often associated with safety issues, identifying potent OAT1 inhibitors with little toxicity is of great value in reducing OAT1-mediat...

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Hlavní autoři: An, Guohua, Wang, Xiaodong, Morris, Marilyn E.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152875/
https://ncbi.nlm.nih.gov/pubmed/25002746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.059337
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