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Crystal structure of the WOPR-DNA complex and implications for Wor1 function in white-opaque switching of Candida albicans

Wor1 (white-opaque switching regulator 1) is a master regulator of the white-opaque switching in Candida albicans, an opportunistic human fungal pathogen, and is associated with its pathogenicity and commensality. Wor1 contains a conserved DNA-binding region at the N-terminus, consisting of two cons...

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Detalhes bibliográficos
Main Authors: Zhang, Shicheng, Zhang, Tianlong, Yan, Minghui, Ding, Jianping, Chen, Jiangye
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152732/
https://ncbi.nlm.nih.gov/pubmed/25091450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.102
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