Characterisation of bla(TEM) genes and types of β-lactamase plasmids in Neisseria gonorrhoeae – the prevalent and conserved bla(TEM-135) has not recently evolved and existed in the Toronto plasmid from the origin

BACKGROUND: Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a major concern worldwide. It has been recently feared that the bla(TEM-1) gene is, via bla(TEM-135), evolving into an extended-spectrum β-lactamase (ESBL), which could degrade all cephalosporins including ceftriaxone. The aims o...

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Main Authors: Muhammad, Ibrahim, Golparian, Daniel, Dillon, Jo-Anne R, Johansson, Åsa, Ohnishi, Makoto, Sethi, Sunil, Chen, Shao-chun, Nakayama, Shu-ichi, Sundqvist, Martin, Bala, Manju, Unemo, Magnus
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152594/
https://ncbi.nlm.nih.gov/pubmed/25149062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-14-454
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