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Genetic instability of M protein and serum opacity factor of group A streptocci: evidence suggesting extrachromosomal control.

The M antigen, a primary determinant of virulence in group A streptococci that is expressed biologically as resistance to phagocytosis, is known to undergo a variety of phenotypic changes both in vivo and in vitro. These changes are nonrandom and can occur at a high frequency. Using the previously d...

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Detalhes bibliográficos
Main Authors: Cleary, P P, Johnson, Z, Wannamaker, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415253/
https://ncbi.nlm.nih.gov/pubmed/1095489
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