ATP hydrolysis reduces neutrophil infiltration and necrosis in partial-thickness scald burns in mice

OBJECTIVE: Extracellular ATP, present in thermally-injured tissue, modulates the inflammatory response and causes significant tissue damage. We hypothesize that neutrophil infiltration and ensuing tissue necrosis would be mitigated by removing ATP-dependent signaling at the burn site. METHODS: Mice...

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Bibliografiske detaljer
Main Authors: Bayliss, Jill, DeLaRosa, Sara, Wu, Jianfeng, Peterson, Jonathan R, Eboda, Oluwatobi N., Su, Grace L, Hemmila, Mark, Krebsbach, Paul H., Cederna, Paul S., Wang, Stewart C, Xi, Chuanwu, Levi, Benjamin
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152376/
https://ncbi.nlm.nih.gov/pubmed/23877144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BCR.0b013e31829b36d6
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