Genome-wide profiling of Hfq-binding RNAs uncovers extensive post-transcriptional rewiring of major stress response and symbiotic regulons in Sinorhizobium meliloti

The RNA chaperone Hfq is a global post-transcriptional regulator in bacteria. Here, we used RNAseq to analyze RNA populations from the legume symbiont Sinorhizobium meliloti that were co-immunoprecipitated (CoIP-RNA) with a FLAG-tagged Hfq in five growth/stress conditions. Hfq-bound transcripts (131...

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Main Authors: Torres-Quesada, Omar, Reinkensmeier, Jan, Schlüter, Jan-Philip, Robledo, Marta, Peregrina, Alexandra, Giegerich, Robert, Toro, Nicolás, Becker, Anke, Jiménez-Zurdo, Jose I
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152363/
https://ncbi.nlm.nih.gov/pubmed/24786641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.28239
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