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mGluR1-Mediated Excitation of Cerebellar GABAergic Interneurons Requires Both G Protein-Dependent and Src–ERK1/2-Dependent Signaling Pathways

Stimulation of type I metabotropic glutamate receptors (mGluR1/5) in several neuronal types induces slow excitatory responses through activation of transient receptor potential canonical (TRPC) channels. GABAergic cerebellar molecular layer interneurons (MLIs) modulate firing patterns of Purkinje ce...

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Autors principals: Kubota, Hideo, Nagao, Soichi, Obata, Kunihiko, Hirono, Moritoshi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152260/
https://ncbi.nlm.nih.gov/pubmed/25181481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106316
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