ALPHA-CTX is associated with subchondral bone turnover and predicts progression of joint space narrowing and osteophytes in osteoarthritis

OBJECTIVE: To evaluate joint tissue remodeling, with urinary collagen biomarkers, uALPHA CTX and uCTXII, and their association with osteoarthritis (OA) severity, progression, and localized knee bone turnover. METHODS: Participants (N=149) with symptomatic and radiographic knee OA underwent fixed fle...

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Main Authors: Huebner, Janet L, Bay-Jensen, Anne C, Huffman, Kim M, He, Yi, Leeming, Diana J, McDaniel, Gary E, Karsdal, Morten A, Kraus, Virginia B
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152234/
https://ncbi.nlm.nih.gov/pubmed/24909851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38739
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