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Bcl-2 Antagonists: A Proof of Concept for CLL Therapy
Defective apoptosis is a fundamental hallmark feature of CLL biology and is a major target of cancer therapy development. High levels of Bcl-2 family anti-apoptotic proteins are considered primarily responsible for inhibiting apoptosis in CLL cells. While several approaches were considered to select...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4152228/ https://ncbi.nlm.nih.gov/pubmed/23907405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-013-0002-4 |
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