Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis

BACKGROUND: Previous studies of immunoglobulin gene sequences in patients with allergic diseases using low-throughput Sanger sequencing have limited the analytic depth for characterization of IgE repertoires. OBJECTIVES: We used a high-throughput, next-generation sequencing approach to characterize...

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Detalhes bibliográficos
Main Authors: Wu, Yu-Chang B., James, Louisa K., Vander Heiden, Jason A., Uduman, Mohamed, Durham, Stephen R., Kleinstein, Steven H., Kipling, David, Gould, Hannah J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mosby 2014
Assuntos:
Rhinitis, Sinusitis, and Upper Airway Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151999/
https://ncbi.nlm.nih.gov/pubmed/25171866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.07.010
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