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Discovery of a novel (R)-selective bacterial hydroxynitrile lyase from Acidobacterium capsulatum
Hydroxynitrile lyases (HNLs) are powerful carbon–carbon bond forming enzymes. The reverse of their natural reaction – the stereoselective addition of hydrogen cyanide (HCN) to carbonyls – yields chiral cyanohydrins, versatile building blocks for the pharmaceutical and chemical industry. Recently, ba...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Research Network of Computational and Structural Biotechnology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151996/ https://ncbi.nlm.nih.gov/pubmed/25210600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2014.07.002 |
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