Tetrameric c-di-GMP Mediates Effective Transcription Factor Dimerization to Control Streptomyces Development

The cyclic dinucleotide c-di-GMP is a signaling molecule with diverse functions in cellular physiology. Here, we report that c-di-GMP can assemble into a tetramer that mediates the effective dimerization of a transcription factor, BldD, which controls the progression of multicellular differentiation...

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Autori principali: Tschowri, Natalia, Schumacher, Maria A., Schlimpert, Susan, Chinnam, Naga babu, Findlay, Kim C., Brennan, Richard G., Buttner, Mark J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151990/
https://ncbi.nlm.nih.gov/pubmed/25171413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.022
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