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Structural basis for heavy metal detoxification by an Atm1-type ABC exporter

While significant progress has been achieved in the structural analysis of exporters from the superfamily of ATP Binding Cassette (ABC) transporters, much less is known about how they selectively recognize substrates and how substrate binding is coupled to ATP hydrolysis. We have addressed these que...

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Detalhes bibliográficos
Main Authors: Lee, Jonas Y., Yang, Janet G., Zhitnitsky, Daniel, Lewinson, Oded, Rees, Douglas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151877/
https://ncbi.nlm.nih.gov/pubmed/24604198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1246489
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