Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial

BACKGROUND: Dalcetrapib modulates cholesteryl ester transfer protein (CETP) activity to raise high-density lipoprotein cholesterol (HDL-C). After the failure of torcetrapib it was unknown if HDL produced by interaction with CETP had pro-atherogenic or pro-inflammatory properties. dal-PLAQUE is the f...

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Main Authors: Fayad, Zahi A, Mani, Venkatesh, Woodward, Mark, Kallend, David, Abt, Markus, Burgess, Tracy, Fuster, Valentin, Ballantyne, Christie M, Stein, Evan A, Tardif, Jean-Claude, Rudd, James H F, Farkouh, Michael E, Tawakol, Ahmed
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151875/
https://ncbi.nlm.nih.gov/pubmed/21908036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(11)61383-4
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