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Nicotinamide Rescues Human Embryonic Stem Cell-Derived Neuroectoderm from Parthanatic Cell Death

Abundant cell death is observed when human embryonic stem cells (hESCs) undergo neuralization, a critical first step for future cell-based therapies addressing neurodegeneration. Using hESC neuralization as an in vitro model of human development, we demonstrated that the developing neuroepithelium a...

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Detalhes bibliográficos
Main Authors: Cimadamore, Flavio, Curchoe, Carol Lynn, Alderson, Nazilla, Scott, Fiona, Salvesen, Guy, Terskikh, Alexey V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151857/
https://ncbi.nlm.nih.gov/pubmed/19544437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.107
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