A novel cancer vaccine strategy with combined IL-18 and HSV-TK gene therapy driven by the hTERT promoter in a murine colorectal cancer model

A therapeutic vaccine against minimal residual cancer cells is needed for the treatment of patients with colorectal cancer. Several gene therapy studies have revealed that the combination of a suicide gene and cytokine gene might induce effective antitumor immunity. In this study, we constructed an...

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Главные авторы: HIGASHI, KOSUKE, HAZAMA, SHOICHI, ARAKI, ATSUHIRO, YOSHIMURA, KIYOSHI, IIZUKA, NORIO, YOSHINO, SHIGEFUMI, NOMA, TAKAFUMI, OKA, MASAKI
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2014
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151806/
https://ncbi.nlm.nih.gov/pubmed/25051201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2557
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