Ubiquitin-proteasomal degradation of antiapoptotic survivin facilitates induction of apoptosis in prostate cancer cells by pristimerin

Pristimerin (PM), a quinonemethide triterpenoid, is a promising anticancer agent with potent antiproliferative and apoptosis-inducing activities against cancer cell lines. However, the anticancer activity and mechanisms of PM in prostate cancer cells have not been adequately investigated. Here we re...

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Bibliographic Details
Main Authors: LIU, YONG BO, GAO, XIAOHUA, DEEB, DORAH, BRIGOLIN, CHRIS, ZHANG, YIGUAN, SHAW, JIAJIU, PINDOLIA, KIRIT, GAUTAM, SUBHASH C.
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2014
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151800/
https://ncbi.nlm.nih.gov/pubmed/25175770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2561
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