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Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5

A challenge for microbial pathogens is to assure that their translocated effector proteins target only the correct host cell compartment during infection. The Legionella pneumophila effector vacuolar protein sorting inhibitor protein D (VipD) localizes to early endosomal membranes and alters their l...

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Bibliografiske detaljer
Main Authors: Lucas, María, Gaspar, Andrew H., Pallara, Chiara, Rojas, Adriana Lucely, Fernández-Recio, Juan, Machner, Matthias P., Hierro, Aitor
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151760/
https://ncbi.nlm.nih.gov/pubmed/25114243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405391111
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