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Interleukin-1 deficiency prolongs ovarian lifespan in mice

Oocyte endowment dwindles away during prepubertal and adult life until menopause occurs, and apoptosis has been identified as a central mechanism responsible for oocyte elimination. A few recent reports suggest that uncontrolled inflammation may adversely affect ovarian reserve. We tested the possib...

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Hlavní autoři: Uri-Belapolsky, Shiri, Shaish, Aviv, Eliyahu, Efrat, Grossman, Hadas, Levi, Mattan, Chuderland, Dana, Ninio-Many, Lihi, Hasky, Noa, Shashar, David, Almog, Tal, Kandel-Kfir, Michal, Harats, Dror, Shalgi, Ruth, Kamari, Yehuda
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151745/
https://ncbi.nlm.nih.gov/pubmed/25114230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323955111
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