The histamine H(4) receptor mediates inflammation and Th17 responses in preclinical models of arthritis

OBJECTIVE: The histamine H(4) receptor (H(4)R) has been shown to drive inflammatory responses in models of asthma, colitis and dermatitis, and in these models it appears to affect both innate and adaptive immune responses. In this study, we used both H(4)R-deficient mice and a specific H(4)R antagon...

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Detalhes bibliográficos
Main Authors: Cowden, Jeffery M, Yu, Fuqu, Banie, Homayon, Farahani, Mandana, Ling, Ping, Nguyen, Steven, Riley, Jason P, Zhang, Mai, Zhu, Jian, Dunford, Paul J, Thurmond, Robin L
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Basic and Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151522/
https://ncbi.nlm.nih.gov/pubmed/24126456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-203832
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