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Using ChIP-Seq Technology to Generate High-Resolution Profiles of Histone Modifications

The dynamic modification of DNA and histones plays a key role in transcriptional regulation through altering the packaging of DNA and modifying the nucleosome surface. These chromatin states, also referred to as the epigenome, are distinctive for different tissues, developmental stages, and disease...

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Main Authors: O’Geen, Henriette, Echipare, Lorigail, Farnham, Peggy J.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151291/
https://ncbi.nlm.nih.gov/pubmed/21913086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-316-5_20
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