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In search of a surrogate: engineering human beta cell lines for therapy

Replacement of insulin-producing cells is a promising therapy for the restoration of the beta cell mass that is destroyed in patients with type 1 diabetes (T1D). However, the use of large amounts of islets per transplant, coupled with the scarcity of donor tissue, diminishes its feasibility. Here we...

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Detalhes bibliográficos
Main Authors: Newby, Brittney N., Terada, Naohiro, Mathews, Clayton E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151247/
https://ncbi.nlm.nih.gov/pubmed/24958526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2014.05.006
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