Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor.

The low-density lipoprotein (LDL) receptor plays a central role in mammalian cholesterol metabolism, clearing lipoproteins which bear apolipoproteins E and B-100 from plasma. Mutations in this molecule are associated with familial hypercholesterolemia, a condition which leads to an elevated plasma c...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Daly, N L, Scanlon, M J, Djordjevic, J T, Kroon, P A, Smith, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41512/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7603991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.14.6334
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