Oncogenic RIT1 mutations in lung adenocarcinoma

Lung adenocarcinoma is comprised of distinct mutational subtypes characterized by mutually exclusive oncogenic mutations in RTK/RAS pathway members KRAS, EGFR, BRAF and ERBB2, and translocations involving ALK, RET and ROS1. Identification of these oncogenic events has transformed the treatment of lu...

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Hlavní autoři: Berger, A H, Imielinski, M, Duke, F, Wala, J, Kaplan, N, Shi, G-X, Andres, D A, Meyerson, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150988/
https://ncbi.nlm.nih.gov/pubmed/24469055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.581
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