Diet control to achieve euglycemia induces significant loss of heart and liver weight via increased autophagy compared with ad libitum diet in diabetic rats

Intensive glucose control increases the all-cause mortality in type 2 diabetes mellitus (T2DM); however, the underlying mechanisms remain unclear. We hypothesized that strict diet control to achieve euglycemia in diabetes damages major organs, increasing the mortality risk. To evaluate effects on ma...

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Main Authors: Lee, Jun-Ho, Lee, Ju-Han, Jin, Mingli, Han, Sang-Don, Chon, Gyu-Rak, Kim, Ick-Hee, Kim, Seonguk, Kim, Sung-Young, Choi, Soo-Bong, Noh, Yun-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150935/
https://ncbi.nlm.nih.gov/pubmed/25168310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.52
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