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TETHERED-BEAD, IMMUNE SANDWICH ASSAY

We describe a proof-of-principal, immune sandwich assay in which immune complexes link micron-size beads via DNA tethers to a sensor surface. The number of tethered beads, counted using low-magnification microscopy, provides a measure of the concentration of analyte. The prototype assay was sensitiv...

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Detalhes bibliográficos
Main Authors: Silver, Jonathan, Li, Zhenyu, Neuman, Keir
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150821/
https://ncbi.nlm.nih.gov/pubmed/25064819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bios.2014.07.011
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