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The telomeric protein Pot1 from Schizosaccharomyces pombe binds ssDNA in two modes with differing 3′ end availability

Telomere protection and length regulation are important processes for aging, cancer and several other diseases. At the heart of these processes lies the single-stranded DNA (ssDNA)-binding protein Pot1, a component of the telomere maintenance complex shelterin, which is present in species ranging fr...

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Bibliographic Details
Main Authors: Dickey, Thayne H., Wuttke, Deborah S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150783/
https://ncbi.nlm.nih.gov/pubmed/25074378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku680
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