Extensive remodeling of DC function by rapid maturation-induced transcriptional silencing

The activation, or maturation, of dendritic cells (DCs) is crucial for the initiation of adaptive T-cell mediated immune responses. Research on the molecular mechanisms implicated in DC maturation has focused primarily on inducible gene-expression events promoting the acquisition of new functions, s...

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Détails bibliographiques
Auteurs principaux: Seguín-Estévez, Queralt, Dunand-Sauthier, Isabelle, Lemeille, Sylvain, Iseli, Christian, Ibberson, Mark, Ioannidis, Vassilios, Schmid, Christoph D., Rousseau, Philippe, Barras, Emmanuèle, Geinoz, Antoine, Xenarios, Ioannis, Acha-Orbea, Hans, Reith, Walter
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Gene regulation, Chromatin and Epigenetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150779/
https://ncbi.nlm.nih.gov/pubmed/25104025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku674
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