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Rare Mutations of Peroxisome Proliferator-Activated Receptor Gamma: Frequencies and Relationship with Insulin Resistance and Diabetes Risk in the Mixed Ancestry Population from South Africa

Background. Genetic variants in the nuclear transcription receptor, PPARG, are associated with cardiometabolic traits, but reports remain conflicting. We determined the frequency and the clinical relevance of PPARG SNPs in an African mixed ancestry population. Methods. In a cross-sectional study, 82...

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Detalhes bibliográficos
Main Authors: Vergotine, Z., Kengne, A. P., Erasmus, R. T., Yako, Y. Y., Matsha, T. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150434/
https://ncbi.nlm.nih.gov/pubmed/25197274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/187985
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