A CD8 T-Cell Epitope Variant Enhances Immune Targeting to a Recombinant Picornavirus Vaccine Antigen

Recombinant virus vaccines are often less effective due to immunodominant responses against endogenous vector antigens. However, the use of small RNA virus vectors provides an opportunity to limit host exposure to endogenous virus antigens and focus immune responses on the desired vaccine antigen. U...

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Detaylı Bibliyografya
Asıl Yazarlar: Bell, Michael P., Renner, Danielle N., Johnson, Aaron J., Pavelko, Kevin D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2014
Konular:
Brief Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150375/
https://ncbi.nlm.nih.gov/pubmed/25025983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2014.0045
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