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GH Dysfunction in Engrailed-2 Knockout Mice, a Model for Autism Spectrum Disorders
Insulin-like growth factor 1 (IGF-1) signaling promotes brain development and plasticity. Altered IGF-1 expression has been associated to autism spectrum disorders (ASD). IGF-1 levels were found increased in the blood and decreased in the cerebrospinal fluid of ASD children. Accordingly, IGF-1 treat...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150208/ https://ncbi.nlm.nih.gov/pubmed/25225635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2014.00092 |
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