Role of GnRH receptor mutations in patients with a wide spectrum of pubertal delay

OBJECTIVE: To analyze the GNRHR in patients with normosmic isolated hypogonadotropic hypogonadism (IHH) and constitutional delay of growth and puberty (CDGP). DESIGN: Molecular analysis and in vitro experiments correlated with phenotype. SETTING: Academic medical center. PATIENT(S): 110 individuals...

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Main Authors: Beneduzzi, Daiane, Trarbach, Ericka B., Min, Le, Jorge, Alexander A. L., Garmes, Heraldo M., Renk, Alessandra Covallero, Fichna, Marta, Fichna, Piotr, Arantes, Karina A., Costa, Elaine M. F., Zhang, Anna, Adeola, Oluwaseun, Wen, Junping, Carroll, Rona S., Mendonça, Berenice B., Kaiser, Ursula B., Latronico, Ana Claudia, Silveira, Letícia F. G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149947/
https://ncbi.nlm.nih.gov/pubmed/25016926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2014.05.044
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