Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals

Gene variants found to associate with human longevity in one population rarely replicate in other populations. The lack of consistent findings may partly be explained by genetic heterogeneity among long-lived individuals due to cohort differences in survival probability. In most high-income countrie...

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Main Authors: Nygaard, Marianne, Lindahl-Jacobsen, Rune, Soerensen, Mette, Mengel-From, Jonas, Andersen-Ranberg, Karen, Jeune, Bernard, Vaupel, James W., Tan, Qihua, Christiansen, Lene, Christensen, Kaare
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149928/
https://ncbi.nlm.nih.gov/pubmed/24809632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.04.018
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