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Looking Beneath the Surface to Determine What Makes DNA Damage Deleterious
Apurinic/apyrimidinic and oxidized abasic sites are chemically reactive DNA lesions that are produced by a variety of damaging agents. The effects of these molecules that lack a Watson-Crick base on polymerase enzymes are well documented. More recently, multiple consequences of the electrophilic nat...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149920/ https://ncbi.nlm.nih.gov/pubmed/24762292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.03.018 |
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