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A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development

Recent evidence suggests that ovarian high-grade serous carcinoma (HGSC) originates from the epithelium of the fallopian tube. However, most mouse models are based on the previous prevailing view that ovarian cancer develops from the transformation of the ovarian surface epithelium. Here, we report...

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Bibliografiska uppgifter
Huvudupphovsmän: Sherman-Baust, Cheryl A., Kuhn, Elisabetta, Valle, Blanca L., Shih, Ie-Ming, Kurman, Robert J., Wang, Tian-Li, Amano, Tomokazu, Ko, Minoru S.H., Miyoshi, Ichiro, Araki, Yoshihiko, Lehrmann, Elin, Zhang, Yongqing, Becker, Kevin G., Morin, Patrice J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149901/
https://ncbi.nlm.nih.gov/pubmed/24652535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4353
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