A chemical potentiator of copper-accumulation used to investigate the iron-regulons of Saccharomyces cerevisiae

The extreme resistance of Saccharomyces cerevisiae to copper is overcome by 2-(6-benzyl-2-pyridyl)quinazoline (BPQ), providing a chemical-biology tool which has been exploited in two lines of discovery. First, BPQ is shown to form a red (BPQ)(2)Cu(I) complex and promote Ctr1-independent copper-accum...

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Main Authors: Foster, Andrew W, Dainty, Samantha J, Patterson, Carl J, Pohl, Ehmke, Blackburn, Hannah, Wilson, Clare, Hess, Corinna R, Rutherford, Julian C, Quaranta, Laura, Corran, Andy, Robinson, Nigel J
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2014
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149784/
https://ncbi.nlm.nih.gov/pubmed/24895027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12661
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