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Psychedelic N,N-Dimethyltryptamine and 5-Methoxy-N,N-Dimethyltryptamine Modulate Innate and Adaptive Inflammatory Responses through the Sigma-1 Receptor of Human Monocyte-Derived Dendritic Cells

The orphan receptor sigma-1 (sigmar-1) is a transmembrane chaperone protein expressed in both the central nervous system and in immune cells. It has been shown to regulate neuronal differentiation and cell survival, and mediates anti-inflammatory responses and immunosuppression in murine in vivo mod...

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Detalhes bibliográficos
Main Authors: Szabo, Attila, Kovacs, Attila, Frecska, Ede, Rajnavolgyi, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149582/
https://ncbi.nlm.nih.gov/pubmed/25171370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106533
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