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Interaction with the recombination hot spot chi in vivo converts the RecBCD enzyme of Escherichia coli into a chi-independent recombinase by inactivation of the RecD subunit.

The RecBCD enzyme of Escherichia coli promotes recombination preferentially at chi nucleotide sequences and has in vivo helicase and strong duplex DNA exonuclease (exoV) activities. The enzyme without the RecD subunit, as in a recD null mutant, promotes recombination efficiently but independently of...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Köppen, A, Krobitsch, S, Thoms, B, Wackernagel, W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41495/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7541534/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.14.6249
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