Upregulation of ERK1/2-eNOS via AT2 Receptors Decreases the Contractile Response to Angiotensin II in Resistance Mesenteric Arteries from Obese Rats

It has been clearly established that mitogen-activated protein kinases (MAPKS) are important mediators of angiotensin II (Ang II) signaling via AT1 receptors in the vasculature. However, evidence for a role of these kinases in changes of Ang II-induced vasoconstriction in obesity is still lacking. H...

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Detalhes bibliográficos
Main Authors: Hagihara, Graziela N., Lobato, Nubia S., Filgueira, Fernando P., Akamine, Eliana H., Aragão, Danielle S., Casarini, Dulce E., Carvalho, Maria Helena C., Fortes, Zuleica B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149482/
https://ncbi.nlm.nih.gov/pubmed/25170617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106029
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