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Overexpression of Atypical Protein Kinase C in HeLa Cells Facilitates Macropinocytosis via Src Activation

Atypical protein kinase C (aPKC) is the first recognized kinase oncogene. However, the specific contribution of aPKC to cancer progression is unclear. The pseudosubstrate domain of aPKC is different from the other PKC family members, and therefore a synthetic peptide corresponding to the aPKC pseudo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tisdale, Ellen J., Shisheva, Assia, Artalejo, Cristina R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149413/
https://ncbi.nlm.nih.gov/pubmed/24582589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.02.014
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