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Update on the Use of l-Asparaginase in Infants and Adolescent Patients with Acute Lymphoblastic Leukemia

Great improvements have been made in acute lymphoblastic leukemia (ALL) treatment in the past decades, especially due to the use of l-asparaginase (l-ASP). Despite the significant success rate, several side effects mainly caused by toxicity, asparaginase silent inactivation, and cellular resistance,...

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Main Authors: Andrade, Augusto F, Borges, Kleiton S, Silveira, Vanessa S
Format: Artigo
Jezik:Inglês
Izdano: Libertas Academica 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149393/
https://ncbi.nlm.nih.gov/pubmed/25210485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMO.S10242
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