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Enteric Bacterial Metabolites Propionic and Butyric Acid Modulate Gene Expression, Including CREB-Dependent Catecholaminergic Neurotransmission, in PC12 Cells - Possible Relevance to Autism Spectrum Disorders

Alterations in gut microbiome composition have an emerging role in health and disease including brain function and behavior. Short chain fatty acids (SCFA) like propionic (PPA), and butyric acid (BA), which are present in diet and are fermentation products of many gastrointestinal bacteria, are show...

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Détails bibliographiques
Auteurs principaux: Nankova, Bistra B., Agarwal, Raj, MacFabe, Derrick F., La Gamma, Edmund F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149359/
https://ncbi.nlm.nih.gov/pubmed/25170769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103740
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