The distribution of insertionally polymorphic endogenous retroviruses in breast cancer patients and cancer-free controls

BACKGROUND: Integration of retroviral DNA into a germ cell can result in a provirus that is transmitted vertically to the host’s offspring. In humans, such endogenous retroviruses (HERVs) comprise >8% of the genome. The HERV-K(HML-2) proviruses consist of ~90 elements related to mouse mammary tum...

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Main Authors: Wildschutte, Julia H, Ram, Daniel, Subramanian, Ravi, Stevens, Victoria L, Coffin, John M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149278/
https://ncbi.nlm.nih.gov/pubmed/25112280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0062-3
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