Influence of multiple APOE genetic variants on cognitive function in a cohort of older men – results from the Normative Aging Study

BACKGROUND: APOE is the biomarker with the greatest known influence on cognitive function; however, the effect of complex haplotypes involving polymorphisms rs449647, rs405509, rs440446, rs429358 and rs7412 has never been studied in older populations. METHODS: We evaluated APOE polymorphisms using m...

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Detalhes bibliográficos
Main Authors: Prada, Diddier, Colicino, Elena, Power, Melinda C, Cox, David G, Weisskopf, Marc G, Hou, Lifang, Spiro III, Avron, Vokonas, Pantel, Zhong, Jia, Sanchez-Guerra, Marco, Herrera, Luis A, Schwartz, Joel, Baccarelli, Andrea A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149270/
https://ncbi.nlm.nih.gov/pubmed/25085564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-014-0223-x
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