Systemic delivery of P42 peptide: a new weapon to fight Huntington’s disease

BACKGROUND: In Huntington’s disease (HD), the ratio between normal and mutant Huntingtin (polyQ-hHtt) is crucial in the onset and progression of the disease. As a result, addition of normal Htt was shown to improve polyQ-hHtt-induced defects. Therefore, we recently identified, within human Htt, a 23...

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Autores principales: Arribat, Yoan, Talmat-Amar, Yasmina, Paucard, Alexia, Lesport, Pierre, Bonneaud, Nathalie, Bauer, Caroline, Bec, Nicole, Parmentier, Marie-Laure, Benigno, Lorraine, Larroque, Christian, Maurel, Patrick, Maschat, Florence
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149238/
https://ncbi.nlm.nih.gov/pubmed/25091984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0086-x
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