Altered distribution of the EphA4 kinase in hippocampal brain tissue of patients with Alzheimer’s disease correlates with pathology

Synaptic dysfunction occurs early in the progression of Alzheimer’s disease (AD) and correlates with memory decline. There is emerging evidence that deregulation of Erythropoietin-producing hepatocellular (Eph) receptor tyrosine kinases (RTK) signaling contributes to the aberrant synaptic functions...

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Detalhes bibliográficos
Main Authors: Rosenberger, Andrea FN, Rozemuller, Annemieke JM, van der Flier, Wiesje M, Scheltens, Philip, van der Vies, Saskia M, Hoozemans, Jeroen JM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149234/
https://ncbi.nlm.nih.gov/pubmed/25027113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0079-9
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