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Correlates to Increased Lethality of Attenuated Venezuelan Encephalitis Virus Vaccine for Immunosuppressed Hamsters

Splenectomy or pretreatment of adult hamsters with cyclophosphamide (Cytoxan) increased the lethality of the TC-83 vaccine strain of Venezuelan encephalitis virus (VEE), inoculated subcutaneously, from 12% for normal hamsters to 75 and 76%, respectively. Neither splenectomy nor cyclophosphamide trea...

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Autors principals: Jahrling, Peter B., Dendy, Earl, Eddy, Gerald A.
Format: Artigo
Idioma:Inglês
Publicat: 1974
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC414907/
https://ncbi.nlm.nih.gov/pubmed/4824635
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