Correlates to Increased Lethality of Attenuated Venezuelan Encephalitis Virus Vaccine for Immunosuppressed Hamsters

Splenectomy or pretreatment of adult hamsters with cyclophosphamide (Cytoxan) increased the lethality of the TC-83 vaccine strain of Venezuelan encephalitis virus (VEE), inoculated subcutaneously, from 12% for normal hamsters to 75 and 76%, respectively. Neither splenectomy nor cyclophosphamide trea...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Jahrling, Peter B., Dendy, Earl, Eddy, Gerald A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1974
Assuntos:	Viral Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC414907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4824635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.9.5.924-930.1974
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